Echogenic foci in thyroid nodules: diagnostic performance with combination of TIRADS and echogenic foci

BMC Medical Imaging

Table 4 Diagnostic Performance of US Characteristics for the Prediction of Malignancy in Thyroid Nodules with Echogenic foci Types with TIRADS Combination (High suspicion)

Echogenic foci	TIRADS	Total	Benign	Malignant	Diagnostic Performance
Echogenic foci	TIRADS	Total	Benign	Malignant	Sensitivity	Specificity	Accuracy	PPV	NPV
Type 1	+ Web-based TIRADS (≥ 8)	148	14	134	52.8	89.7	65.6	90.5	50.4
	+ K-TIRADS High Suspicion	156	19	137	53.9	86.0	65.1	87.8	50.0
	+ ATA High Suspicion	163	21	142	66.7	69.6	67.4	87.1	40.3
	+ Russ et al. (≥ 4B)	189	41	148	58.3	69.9	62.3	78.3	47.3
Type 2	+ Web-based TIRADS (≥ 8)	37	3	34	22.2	94.4	41.1	91.9	30.0
	+K-TIRADS High Suspicion	40	6	34	22.2	88.9	39.6	85.0	28.7
	+ ATA High Suspicion	46	7	39	27.1	75.9	35.3	84.8	17.3
	+ Russ et al. (≥ 4B)	47	8	39	25.5	85.2	41.1	83.0	28.8
Type 3	+ Web-based TIRADS (≥ 8)	22	2	20	7.9	98.5	39.5	90.9	36.4
	+K-TIRADS High Suspicion	37	6	31	12.2	95.6	41.3	83.8	36.8
	+ ATA High Suspicion	38	6	32	15.0	91.3	33.7	84.2	25.8
	+ Russ et al. (≥ 4B)	49	13	36	14.2	90.4	40.8	73.5	36.1
Type 4	+ Web-based TIRADS (≥ 8)	2	1	1	0.4	99.3	34.9	50.0	34.8
	+K-TIRADS High Suspicion	4	1	3	1.2	99.3	35.4	75.0	35.0
	+ ATA High Suspicion	4	1	3	1.4	98.6	25.2	75.0	24.5
	+ Russ et al. (≥ 4B)	6	2	4	1.6	98.5	35.4	66.7	34.9
Type 5	+ Web-based TIRADS (≥ 8)	6	2	4	1.6	98.5	35.4	66.7	34.9
	+K-TIRADS High Suspicion	5	1	4	1.6	99.3	35.6	80.0	35.1
	+ ATA High Suspicion	5	1	4	1.9	98.6	25.5	80.0	24.5
	+ Russ et al. (≥ 4B)	6	2	4	1.6	98.5	35.4	66.7	34.9
Type 6	+ Web-based TIRADS (≥ 8)	21	2	19	7.5	98.5	39.2	90.5	36.3
	+K-TIRADS High Suspicion	24	1	23	9.1	99.3	40.5	95.8	36.9
	+ ATA High Suspicion	25	1	24	11.3	98.6	32.6	96.0	26.5
	+ Russ et al. (≥ 4B)	28	3	25	9.8	97.8	40.5	89.3	36.7

TIRADS thyroid image reporting and data system, ATA american thyroid association, PPV positive predictive value, NPV negative predictive value
Type 1 = Punctate echogenic foci (≤ 1 mm) with or without posterior shadowing
Type 2 = Punctate echogenic foci with comet-tail artifact
Type 3 = Large echogenic foci (> 1 mm) without shadowing
Type 4 = Macrocalcification (defined as large echogenic foci (> 1 mm) with shadowing)
Type 5 = Peripheral curvilinear or eggshell echogenic foci with or without shadowing
Type 6 = Nodules with more than one type of echogenic foci

ISSN: 1471-2342